Misunderstandings and controversies in the diagnosis and treatment of optic nerve sheath meningioma_Chinese Journal of Ocular Fundus Diseases

Authors：

Liu Yi ,  Jiang Libin

Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China;

Corresponding author：

Jiang Libin, Email: jlbjlb@sina.com

Keywords：

Optic nerve neoplasms; Diagnosis; Therapy; Review

DOI：

10.3760/cma.j.cn511434-20200708-00325

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Optic nerve sheath meningiomas (ONSM) account for about 1%-2% of all meningiomas. Most of them are benign and the disease progresses slowly. ONSM is a relatively rare intraorbital benign tumor in clinical practice. Due to its close relationship with the optic nerve, the diagnosis and treatment are special, so there are many controversies and misunderstandings in the diagnosis and treatment of ONSM. ONSM is often misdiagnosed as acute optic nerve papillitis, optic nerve atrophy, ischemic optic neuropathy, acute retrobolic optic neuritis, optic disc vasculitis or optic fatigue due to its similar clinical features to other optic nerve diseases such as optic neuritis. The treatment includes observation, surgical treatment and radiotherapy, and appropriate treatment should be selected for different patients according to the changes of their condition. Therefore, understanding of the controversies and misunderstandings in the diagnosis and treatment of ONSM is of great clinical significance for timely and accurate diagnosis, appropriate treatment and improvement of the prognosis of patients.

Citation： Liu Yi, Jiang Libin. Misunderstandings and controversies in the diagnosis and treatment of optic nerve sheath meningioma. Chinese Journal of Ocular Fundus Diseases, 2021, 37(10): 817-820. doi: 10.3760/cma.j.cn511434-20200708-00325 Copy

1.	Kahraman-Koytak P, Bruce BB, Peragallo JH, et al. Diagnostic errors in initial misdiagnosis of optic nerve sheath meningiomas[J]. JAMA Neurol, 2019, 76(3): 326-332. DOI: 10.1001/jamaneurol.2018.3989.
2.	Misra S, Misra N, Gogri P, et al. A rare case of bilateral optic nerve sheath meningioma[J]. Indian J Ophthalmol, 2014, 62(6): 728-730. DOI: 10.4103/0301-4738.136238.
3.	Kheir V, Faouzi M, Borruat FX. Visual outcomes of fractionated radiotherapy in optic nerve sheath meningioma: a retrospective study[J]. Klin Monbl Augenheilkd, 2019, 236(4): 526-529. DOI: 10.1055/a-0828-7335.
4.	Parker RT, Ovens CA, Fraser CL, et al. Optic nerve sheath meningiomas: prevalence, impact, and management strategies[J]. Eye Brain, 2018, 10: 85-99. DOI: 10.2147/EB.S144345.
5.	Bloch O, Sun M, Kaur G, et al. Fractionated radiotherapy for optic nerve sheath meningiomas[J]. J Clin Neurosci, 2012, 19(9): 1210-1215. DOI: 10.1016/j.jocn.2012.02.010.
6.	Jin J, Joo JD, Han JH, et al. Optic nerve sheath meningioma: preliminary analysis of the role of radiation therapy[J]. Brain Tumor Res Treat, 2018, 6(1): 8-12. DOI: 10.14791/btrt.2018.6.e2.
7.	Rassi MS, Prasad S, Can A, et al. Prognostic factors in the surgical treatment of intracanalicular primary optic nerve sheath meningiomas[J]. J Neurosurg, 2018, 131(2): 481-488. DOI: 10.3171/2018.4.JNS173080.
8.	Alroughani R, Behbehani R. Optic nerve sheath meningioma masquerading as optic neuritis[J/OL]. Case Rep Neurol Med, 2016, 2016: 5419432[2016-01-19]. https://pubmed.ncbi.nlm.nih.gov/26904329/. DOI: 10.1155/2016/5419432.
9.	Mao JF, Xia XB, Tang XB, et al. Analyses on the misdiagnoses of 25 patients with unilateral optic nerve sheath meningioma[J]. Int J Ophthalmol, 2016, 9(9): 1315-1319. DOI: 10.18240/ijo.2016.09.14.
10.	Gündüz K, Catak E, Erden E. Optic nerve biopsy via a medial transconjunctival orbitotomy approach in the diagnosis of optic nerve and sheath tumors[J]. Orbit, 2010, 29(4): 190-193. DOI: 10.3109/01676831003664368.
11.	Metellus P, Kapoor S, Kharkar S, et al. Fractionated conformal radiotherapy for management of optic nerve sheath meningiomas: long-term outcomes of tumor control and visual function at a single institution[J]. Int J Radiat Oncol Biol Phys, 2011, 80(1): 185-192. DOI: 10.1016/j.ijrobp.2010.01.034.
12.	Paulsen F, Doerr S, Wilhelm H, et al. Fractionated stereotactic radiotherapy in patients with optic nerve sheath meningioma[J]. Int J Radiat Oncol Biol Phys, 2012, 82(2): 773-778. DOI: 10.1016/j.ijrobp.2010.11.018.
13.	Liang ZG, Kusumawidjaja G, Kazmi F, et al. Intensity-modulated radiotherapy for paranasal sinuses and base of skull tumors[J]. Oral Oncol, 2018, 86: 61-68. DOI: 10.1016/j.oraloncology.2018.09.010.
14.	Sasano H, Shikishima K, Aoki M, et al. Efficacy of intensity-modulated radiation therapy for optic nerve sheath meningioma[J]. Graefe's Arch Clin Exp Ophthalmol, 2019, 257(10): 2297-2306. DOI: 10.1007/s00417-019-04424-w.
15.	Jacobi DM. Optic nerve sheath meningioma[J]. Clin Exp Optom, 2019, 102(2): 188-190. DOI: 10.1111/cxo.12819.
16.	Ratnayake G, Oh T, Mehta R, et al. Long-term treatment outcomes of patients with primary optic nerve sheath meningioma treated with stereotactic radiotherapy[J]. J Clin Neurosci, 2019, 68: 162-167. DOI: 10.1016/j.jocn.2019.07.005.

1. Kahraman-Koytak P, Bruce BB, Peragallo JH, et al. Diagnostic errors in initial misdiagnosis of optic nerve sheath meningiomas[J]. JAMA Neurol, 2019, 76(3): 326-332. DOI: 10.1001/jamaneurol.2018.3989.
2. Misra S, Misra N, Gogri P, et al. A rare case of bilateral optic nerve sheath meningioma[J]. Indian J Ophthalmol, 2014, 62(6): 728-730. DOI: 10.4103/0301-4738.136238.
3. Kheir V, Faouzi M, Borruat FX. Visual outcomes of fractionated radiotherapy in optic nerve sheath meningioma: a retrospective study[J]. Klin Monbl Augenheilkd, 2019, 236(4): 526-529. DOI: 10.1055/a-0828-7335.
4. Parker RT, Ovens CA, Fraser CL, et al. Optic nerve sheath meningiomas: prevalence, impact, and management strategies[J]. Eye Brain, 2018, 10: 85-99. DOI: 10.2147/EB.S144345.
5. Bloch O, Sun M, Kaur G, et al. Fractionated radiotherapy for optic nerve sheath meningiomas[J]. J Clin Neurosci, 2012, 19(9): 1210-1215. DOI: 10.1016/j.jocn.2012.02.010.
6. Jin J, Joo JD, Han JH, et al. Optic nerve sheath meningioma: preliminary analysis of the role of radiation therapy[J]. Brain Tumor Res Treat, 2018, 6(1): 8-12. DOI: 10.14791/btrt.2018.6.e2.
7. Rassi MS, Prasad S, Can A, et al. Prognostic factors in the surgical treatment of intracanalicular primary optic nerve sheath meningiomas[J]. J Neurosurg, 2018, 131(2): 481-488. DOI: 10.3171/2018.4.JNS173080.
8. Alroughani R, Behbehani R. Optic nerve sheath meningioma masquerading as optic neuritis[J/OL]. Case Rep Neurol Med, 2016, 2016: 5419432[2016-01-19]. https://pubmed.ncbi.nlm.nih.gov/26904329/. DOI: 10.1155/2016/5419432.
9. Mao JF, Xia XB, Tang XB, et al. Analyses on the misdiagnoses of 25 patients with unilateral optic nerve sheath meningioma[J]. Int J Ophthalmol, 2016, 9(9): 1315-1319. DOI: 10.18240/ijo.2016.09.14.
10. Gündüz K, Catak E, Erden E. Optic nerve biopsy via a medial transconjunctival orbitotomy approach in the diagnosis of optic nerve and sheath tumors[J]. Orbit, 2010, 29(4): 190-193. DOI: 10.3109/01676831003664368.
11. Metellus P, Kapoor S, Kharkar S, et al. Fractionated conformal radiotherapy for management of optic nerve sheath meningiomas: long-term outcomes of tumor control and visual function at a single institution[J]. Int J Radiat Oncol Biol Phys, 2011, 80(1): 185-192. DOI: 10.1016/j.ijrobp.2010.01.034.
12. Paulsen F, Doerr S, Wilhelm H, et al. Fractionated stereotactic radiotherapy in patients with optic nerve sheath meningioma[J]. Int J Radiat Oncol Biol Phys, 2012, 82(2): 773-778. DOI: 10.1016/j.ijrobp.2010.11.018.
13. Liang ZG, Kusumawidjaja G, Kazmi F, et al. Intensity-modulated radiotherapy for paranasal sinuses and base of skull tumors[J]. Oral Oncol, 2018, 86: 61-68. DOI: 10.1016/j.oraloncology.2018.09.010.
14. Sasano H, Shikishima K, Aoki M, et al. Efficacy of intensity-modulated radiation therapy for optic nerve sheath meningioma[J]. Graefe's Arch Clin Exp Ophthalmol, 2019, 257(10): 2297-2306. DOI: 10.1007/s00417-019-04424-w.
15. Jacobi DM. Optic nerve sheath meningioma[J]. Clin Exp Optom, 2019, 102(2): 188-190. DOI: 10.1111/cxo.12819.
16. Ratnayake G, Oh T, Mehta R, et al. Long-term treatment outcomes of patients with primary optic nerve sheath meningioma treated with stereotactic radiotherapy[J]. J Clin Neurosci, 2019, 68: 162-167. DOI: 10.1016/j.jocn.2019.07.005.

Chinese Journal of Ocular Fundus Diseases

Misunderstandings and controversies in the diagnosis and treatment of optic nerve sheath meningioma

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content