• 1. Department of Nuclear Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;
  • 2. Department of Nuclear Medicine, People's Hospital of Jianyang, Jiangyang, Sichuan 641400, P. R. China;
TANGGong-shun, Email: tgs010@163.com
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Objective To compare the diagnostic efficacy of serum thyroglobulin (Tg), diagnostic 131I whole-body scan (D-WBS), neck ultrasound for diagnosing metastasis and recurrence of differentiated thyroid carcinoma (DTC). Methods From May to June 2011, fifty follow-up DTC patients were collected retrospectively 6 months or more after 131I ablation therapy following total-thyroidectomy or near-total thyroidectomy. The diagnostic standard for DTC metastasis and relapse were based on serum Tg, D-WBS, neck ultrasound and chest CT. Diagnostic 2 by 2 table was employed for calculating the sensitivity, specificity, accuracy of the methods. Results The sensitivity, specificity, accuracy, positive predictive value, negative predictive value of TgIMA and D-WBS parallel experiments were 100.0%, 92.9%, 96.0%, 91.7%, and 100.0% respectively. Conclusion TgIMA combined with D-WBS parallel test in diagnosis of DTC metastasis and recurrence has the highest accuracy.

Citation: NIJian, WUXia, PANMing-zhi, HUANGRui, TANGGong-shun. Diagnostic Value of Serum Thyroglobulin, Diagnostic 131I Whole-body Scan and Neck Ultrasonography for Evaluation of Lymph Node Metastasis and Recurrence of Differentiated Thyroid Cancer. West China Medical Journal, 2014, 29(1): 34-38. doi: 10.7507/1002-0179.20140010 Copy

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