Progress of Research on Pathogenesis, Prophylaxis and Therapeutics of Pulmonary Infection after Esophageal Cancer Resection_Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Authors：

ZHANG Lin , QI Hai.

Department of Thoracic and Cardiovascular Surgery，Second Affiliated Hospital of XinjiangMedical University，Urumqi 830000，P. R. China;

Corresponding author：

Keywords：

Esophagectomy; 　Pulmonary complication; 　Risk factor

DOI：

10.7507/1007-4848.20130179

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Esophageal cancer is a common gastrointestinal cancer，and the incidence in China is the highest in the world. Esophagectomy represents the gold standard for patients with resectable esophageal cancer，but postoperative morbidity and mortality rates remain high. In recent years，there have been many reports on the pathogenesis of morbidity and mortality after esophagectomy without reaching any concrete conclusion. This review focuses on the pathogenesis，prophylaxis and therapeuticsof pulmonary infection after esophageal cancer resection．

Citation： ZHANG Lin,QI Hai.. Progress of Research on Pathogenesis, Prophylaxis and Therapeutics of Pulmonary Infection after Esophageal Cancer Resection. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2013, 20(5): 588-591. doi: 10.7507/1007-4848.20130179 Copy

1.	Sunpaweravong S， Ruangsin S， Laohawiriyakamol S， et al. Prediction of major postoperative complications and survival for locally advanced esophageal carcinoma patients. Asian J Surg， 2012， 35 （3）：104-109.
2.	Nakamura M， Iwahashi M， Nakamori M， et al. An analysis of the factors contributing to a reduction in the incidence of pulmonary complications following an esophagectomy for esophageal cancer. Langenbecks Arch Surg， 2008， 393 （2）：127-133.
3.	王丽君，顾连兵，蒋大明，等. 食管癌患者术后肺部感染围手术期的影响因素分析. 中华医学杂志， 2012， 92 （19）：1310-1313.
4.	Grotenhuis BA， Wijnhoven BP， Grüne F， et al. Preoperative risk assessment and prevention of complications in patients with esophagealcancer. J Surg Oncol， 2010， 101 （3）：270-278.
5.	Cijs TM， Verhoef C， Steyerberg EW， et al. Outcome of esophagectomy for cancer in elderly patients. Ann Thorac Surg， 2010， 90 （3）：900-907.
6.	Blom RL， Lagarde SM， Klinkenbijl JH， et al. A high body mass index in esophageal cancer patients does not influence postoperativeoutcome or long-term survival. Ann Surg Oncol， 2012， 19 （3）：766-771.
7.	Madani K， Zhao R， Lim HJ， et al. Obesity is not associated with adverse outcome following surgical resection of oesophageal adenocarcinoma. Eur J Cardiothorac Surg， 2010， 38 （5）：604-608.
8.	Akutsu Y， Matsubara H. Perioperative management for the preven-tion of postoperative pneumonia with esophageal surgery. Ann ThoracCardiovasc Surg， 2009， 15 （5）：280-285.
9.	Jiao WJ， Wang TY， Gong M， et al. Pulmonary complications inpatients with chronic obstructive pulmonary disease following transth-oracic esophagectomy. World J Gastroenterol， 2006， 12 （16）：2505-2509.
10.	Win T， Respir JA， Sharples L， et al. Relationship between pulmonary function and lung cancer surgical outcome. Eur Respir J， 2005， 25 （4）：594-599.
11.	Bagheri R， RajabiMashhadi MT， Ghazvini K， et al. The effect of neoadjuvant chemoradiotherapy on airway colonization and postoperative respiratory complications in patients undergoing oesophagectomy for oesophageal cancer. Interact cardiovasc Thorac Surg， 2012， 14 （6）：725-728.
12.	Hurmuzlu M， Øvrebø K， Wentzel-Larsen T， et al. High-dose preo-perative chemoradiotherapy in esophageal cancer patients does not increase postoperative pulmonary complications：correlation with dose-volume histogram parameters. Radiother Oncol， 2010， 97 （1）：60-64.
13.	Ben-David K， Sarosi GA， Cendan JC， et al. Decreasing morbidity and mortality in 100 consecutive minimally invasive esophagectomies.Surg Endosc， 2012， 26 （1）：162-167.
14.	Safranek PM， Cubitt J， Booth MI， et al. Review of open and minimalaccess approaches to oesophagectomy for cancer. Br J Surg， 2010， 97 （12）：1845-1853.
15.	Bakhos CT， Fabian T， Oyasiji TO， et al. Impact of the surgicaltechnique on pulmonary morbidity after esophagectomy. Ann Thorac Surg， 2012， 93 （1）：221-226.
16.	Suttie SA， Nanthakumaran S， Mofidi R， et al. The impact of operativeapproach for oesophageal cancer on outcome：the transhiatal　approach may influence circumferential margin involvement. Eur J Surg Oncol， 2012， 38 （2）：157-165.
17.	Banki F， Mason RJ， DeMeester SR， et al. Vagal-sparing esophag-ectomy：a more physiologic alternative. Ann Surg， 2002， 236 （3）：324-335.
18.	任光国，邓建华，肖波，等. 胸段食管癌喉返神经旁淋巴结转移特点及临床意义. 中华胸心血管外科杂志， 2011， 27 （4）：215-217.
19.	王国磊，陈宇航，刘先本，等. 食管癌术后双侧喉返神经损伤2例. 中华胸心血管外科杂志， 2011， 27 （6）：370.
20.	王见. 高原地区食管癌贲门癌术后肺部感染. 实用肿瘤杂志， 2002， 17 （6）：413-414.
21.	李乃斌，张世范，王云杰，等. 食管癌围术期多脏器功能指标在不同海拔地区的变化及意义. 中华胸心血管外科杂志， 2006， 22 （4）：232-235.
22.	Zingg U， Smithers BM， Gotley DC， et al. Factors associated with postoperative pulmonary morbidity after esophagectomy for cancer. Ann Surg Oncol， 2011， 18 （5）：1460-1468.
23.	Akutsu Y， Matsubara H， Shuto K， et al. Pre-operative dental brushing can reduce the risk of postoperative pneumonia in esophagealcancer patients. Surgery， 2010， 147 （4）：497-502.
24.	Engelman E， Maeyens C. Effect of preoperative single-dose corticos-teroid administration on postoperative morbidity following esopha-gectomy. J Gastrointest Surg， 2010， 14 （5）：788-804.
25.	Sarli D， Bona D， Abraham M， et al. Conservative and surgical treatment of esophago-gastric anastomotic leaks. Ann Ital Chir， 2006， 77 （5）：391-396.
26.	谭军涛. 食管癌术前化放疗的研究进展. 中国癌症防治杂志， 2010， 2 （2）：165-166.
27.	中国抗癌协会食管癌专业委员会，主编. 食管癌规范化诊治指南. 北京：中国协和医科大学出版社， 2011. 99-104.
28.	Tom R， Demeester TR， Barlow AP，et al. Surgery and current management for cancer of the esophagus and cardia. Curr Probl Cancer， 1988， 12 （5）：243-328.
29.	Wei S， Tian J， Song X， et al. Association of perioperative fluid balance and adverse surgical outcomes in esophageal cancer and esophagogastric junction cancer. Ann Thorac Surg， 2008， 86 （1）：266-272.
30.	Lunardi AC， Cecconello I， Carvalho CR. Postoperative chest physicaltherapy prevents respiratory complications in patients undergoing esophagectomy. Rev Bras Fisioter， 2011， 15 （2）：160-165.
31.	Makino H， Kunisaki C， Kosaka T， et al. Perioperative use of a neutrophil elastase inhibitor in video-assisted thoracoscopic oesophagectomy for cancer. Br J Surg， 2011， 98 （7）：975-982.
32.	Kawahara Y， Ninomiya I， Fujimura T， et al. Prospective randomizedcontrolled study on the effects of perioperative administration of a neutrophil elastase inhibitor to patients undergoing video-assisted thoracoscopic surgery for thoracic esophageal cancer. Dis Esophagus，2010， 23 （4）：329-339.
33.	Nishiyama J， Matsuda M， Ando S， et al. The effects of the early administration of sivelestat Sodium， a selective neutrophil elastase inhibitor， on the postoperative course after radical surgery for esop-hageal cancer. Surg Today， 2012， 42 （7）：659-665.
34.	Casado D， López F， Martí R. Perioperative fluid management and major respiratory complications in patients undergoing esophagectomy. Dis Esophagus， 2010， 23 （7）：523-528.

1. 　Sunpaweravong S， Ruangsin S， Laohawiriyakamol S， et al. Prediction of major postoperative complications and survival for locally advanced esophageal carcinoma patients. Asian J Surg， 2012， 35 （3）：104-109.
2. 　Nakamura M， Iwahashi M， Nakamori M， et al. An analysis of the factors contributing to a reduction in the incidence of pulmonary complications following an esophagectomy for esophageal cancer. Langenbecks Arch Surg， 2008， 393 （2）：127-133.
3. 　王丽君，顾连兵，蒋大明，等. 食管癌患者术后肺部感染围手术期的影响因素分析. 中华医学杂志， 2012， 92 （19）：1310-1313.
4. 　Grotenhuis BA， Wijnhoven BP， Grüne F， et al. Preoperative risk assessment and prevention of complications in patients with esophagealcancer. J Surg Oncol， 2010， 101 （3）：270-278.
5. 　Cijs TM， Verhoef C， Steyerberg EW， et al. Outcome of esophagectomy for cancer in elderly patients. Ann Thorac Surg， 2010， 90 （3）：900-907.
6. 　Blom RL， Lagarde SM， Klinkenbijl JH， et al. A high body mass index in esophageal cancer patients does not influence postoperativeoutcome or long-term survival. Ann Surg Oncol， 2012， 19 （3）：766-771.
7. 　Madani K， Zhao R， Lim HJ， et al. Obesity is not associated with adverse outcome following surgical resection of oesophageal adenocarcinoma. Eur J Cardiothorac Surg， 2010， 38 （5）：604-608.
8. 　Akutsu Y， Matsubara H. Perioperative management for the preven-tion of postoperative pneumonia with esophageal surgery. Ann ThoracCardiovasc Surg， 2009， 15 （5）：280-285.
9. 　Jiao WJ， Wang TY， Gong M， et al. Pulmonary complications inpatients with chronic obstructive pulmonary disease following transth-oracic esophagectomy. World J Gastroenterol， 2006， 12 （16）：2505-2509.
10. 　Win T， Respir JA， Sharples L， et al. Relationship between pulmonary function and lung cancer surgical outcome. Eur Respir J， 2005， 25 （4）：594-599.
11. 　Bagheri R， RajabiMashhadi MT， Ghazvini K， et al. The effect of neoadjuvant chemoradiotherapy on airway colonization and postoperative respiratory complications in patients undergoing oesophagectomy for oesophageal cancer. Interact cardiovasc Thorac Surg， 2012， 14 （6）：725-728.
12. 　Hurmuzlu M， Øvrebø K， Wentzel-Larsen T， et al. High-dose preo-perative chemoradiotherapy in esophageal cancer patients does not increase postoperative pulmonary complications：correlation with dose-volume histogram parameters. Radiother Oncol， 2010， 97 （1）：60-64.
13. 　Ben-David K， Sarosi GA， Cendan JC， et al. Decreasing morbidity and mortality in 100 consecutive minimally invasive esophagectomies.Surg Endosc， 2012， 26 （1）：162-167.
14. 　Safranek PM， Cubitt J， Booth MI， et al. Review of open and minimalaccess approaches to oesophagectomy for cancer. Br J Surg， 2010， 97 （12）：1845-1853.
15. 　Bakhos CT， Fabian T， Oyasiji TO， et al. Impact of the surgicaltechnique on pulmonary morbidity after esophagectomy. Ann Thorac Surg， 2012， 93 （1）：221-226.
16. 　Suttie SA， Nanthakumaran S， Mofidi R， et al. The impact of operativeapproach for oesophageal cancer on outcome：the transhiatal　approach may influence circumferential margin involvement. Eur J Surg Oncol， 2012， 38 （2）：157-165.
17. 　Banki F， Mason RJ， DeMeester SR， et al. Vagal-sparing esophag-ectomy：a more physiologic alternative. Ann Surg， 2002， 236 （3）：324-335.
18. 　任光国，邓建华，肖波，等. 胸段食管癌喉返神经旁淋巴结转移特点及临床意义. 中华胸心血管外科杂志， 2011， 27 （4）：215-217.
19. 　王国磊，陈宇航，刘先本，等. 食管癌术后双侧喉返神经损伤2例. 中华胸心血管外科杂志， 2011， 27 （6）：370.
20. 　王见. 高原地区食管癌贲门癌术后肺部感染. 实用肿瘤杂志， 2002， 17 （6）：413-414.
21. 　李乃斌，张世范，王云杰，等. 食管癌围术期多脏器功能指标在不同海拔地区的变化及意义. 中华胸心血管外科杂志， 2006， 22 （4）：232-235.
22. 　Zingg U， Smithers BM， Gotley DC， et al. Factors associated with postoperative pulmonary morbidity after esophagectomy for cancer. Ann Surg Oncol， 2011， 18 （5）：1460-1468.
23. 　Akutsu Y， Matsubara H， Shuto K， et al. Pre-operative dental brushing can reduce the risk of postoperative pneumonia in esophagealcancer patients. Surgery， 2010， 147 （4）：497-502.
24. 　Engelman E， Maeyens C. Effect of preoperative single-dose corticos-teroid administration on postoperative morbidity following esopha-gectomy. J Gastrointest Surg， 2010， 14 （5）：788-804.
25. 　Sarli D， Bona D， Abraham M， et al. Conservative and surgical treatment of esophago-gastric anastomotic leaks. Ann Ital Chir， 2006， 77 （5）：391-396.
26. 　谭军涛. 食管癌术前化放疗的研究进展. 中国癌症防治杂志， 2010， 2 （2）：165-166.
27. 　中国抗癌协会食管癌专业委员会，主编. 食管癌规范化诊治指南. 北京：中国协和医科大学出版社， 2011. 99-104.
28. 　Tom R， Demeester TR， Barlow AP，et al. Surgery and current management for cancer of the esophagus and cardia. Curr Probl Cancer， 1988， 12 （5）：243-328.
29. 　Wei S， Tian J， Song X， et al. Association of perioperative fluid balance and adverse surgical outcomes in esophageal cancer and esophagogastric junction cancer. Ann Thorac Surg， 2008， 86 （1）：266-272.
30. 　Lunardi AC， Cecconello I， Carvalho CR. Postoperative chest physicaltherapy prevents respiratory complications in patients undergoing esophagectomy. Rev Bras Fisioter， 2011， 15 （2）：160-165.
31. 　Makino H， Kunisaki C， Kosaka T， et al. Perioperative use of a neutrophil elastase inhibitor in video-assisted thoracoscopic oesophagectomy for cancer. Br J Surg， 2011， 98 （7）：975-982.
32. 　Kawahara Y， Ninomiya I， Fujimura T， et al. Prospective randomizedcontrolled study on the effects of perioperative administration of a neutrophil elastase inhibitor to patients undergoing video-assisted thoracoscopic surgery for thoracic esophageal cancer. Dis Esophagus，2010， 23 （4）：329-339.
33. 　Nishiyama J， Matsuda M， Ando S， et al. The effects of the early administration of sivelestat Sodium， a selective neutrophil elastase inhibitor， on the postoperative course after radical surgery for esop-hageal cancer. Surg Today， 2012， 42 （7）：659-665.
34. 　Casado D， López F， Martí R. Perioperative fluid management and major respiratory complications in patients undergoing esophagectomy. Dis Esophagus， 2010， 23 （7）：523-528.

Previous Article
胸壁去分化脂肪肉瘤外科治疗一例
Next Article
Progress in Adipose-derived Stromal Cells for the Treatment of Myocardial Infarction

Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Progress of Research on Pathogenesis, Prophylaxis and Therapeutics of Pulmonary Infection after Esophageal Cancer Resection

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content