Quality of life and influencing factors in lung cancer patients after video-assisted thoracic surgery_Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Authors：

TANG Yudong , LUO Ailin , ZHANG Dili , LONG Xingxia , LI Jialu ,  YANG Mei

Department of Thoracic Surgery, West China Hospital, Sichuan University, West China School of Medicine, Sichuan University, West China School of Nursing, Sichuan University, Chengdu, 610041, P. R. China;

Corresponding author：

YANG Mei, Email: yangmei69@126.com

Keywords：

Single-direction video-assisted thoracic surgery; lung cancer; quality of life; influencing factors

DOI：

10.7507/1007-4848.202211010

Video：

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Objective To investigate the short-term quality of life in patients after single-direction video-assisted thoracic surgery (VATS) for lung cancer, and explore the related influencing factors. Methods Patients who underwent single-direction VATS for lung cancer in the Department of Thoracic Surgery, West China Hospital, Sichuan University from July 2020 to August 2021 were continuously selected. The QLQ-C30 and QLQ-LC13 were used to evaluate the quality of life of the patients after the surgery, and the influencing factors were analyzed. Results A total of 193 patients were collected. There were 73 males aged 59.44±11.40 years, and 120 females aged 53.73±11.15 years. The QLQ-C30 score of the patients after single-direction VATS for lung cancer was 69.09±20.21 points. Univariate analysis and Pearson correlation analysis showed that age, occupation, anesthesia time, postoperative complications, postoperative antibiotic use time, postoperative hospital stay, insomnia, economic stress, hemoptysis, chest pain, dysphagia, arm or shoulder pain were associated with the quality of life (P≤0.05). The results of multiple regression analysis showed that anesthesia time, economic pressure, insomnia and chest pain had a significant impact on the overall quality of life 30 days after the surgery (P≤0.05). Conclusion The anesthesia time, economic pressure, insomnia and chest pain are independent influencing factors for the quality of life after the VATS lung cancer surgery.

Citation： TANG Yudong, LUO Ailin, ZHANG Dili, LONG Xingxia, LI Jialu, YANG Mei. Quality of life and influencing factors in lung cancer patients after video-assisted thoracic surgery. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2023, 30(4): 569-575. doi: 10.7507/1007-4848.202211010 Copy

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16.	Wang B, Hao N, Zhang X. Factors influencing the psychology and quality of life in lung cancer patients. Saudi Med J, 2017, 38(9): 948-951.
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28.	Riedl D, Gastl R, Gamper E, et al. Cancer patients’ wish for psychological support during outpatient radiation therapy: Findings from a psychooncological monitoring program in clinical routine. Strahlenther Onkol, 2018, 194(7): 655-663.
29.	朱富忠, 盛奇伟, 顾文英, 等. 社会工作视阈下癌症患者心理支持服务模式. 解放军医院管理杂志, 2017, 24(6): 538-541.
30.	Wang L, Wang Z. Research on the quality hospice care of elderly cancer patients in China under social work intervention. Environ Health Prev Med, 2020, 25(1): 36.
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32.	Mogavero MP, DelRosso LM, Fanfulla F, et al. Sleep disorders and cancer: State of the art and future perspectives. Sleep Med Rev, 2021, 56: 101409.
33.	Anderson KO, Getto CJ, Mendoza TR, et al. Fatigue and sleep disturbance in patients with cancer, patients with clinical depression, and community-dwelling adults. J Pain Symptom Manage, 2003, 25(4): 307-318.
34.	Koch M, Hjermstad MJ, Tomaszewski K, et al. Gender effects on quality of life and symptom burden in patients with lung cancer: Results from a prospective, cross-cultural, multi-center study. J Thorac Dis, 2020, 12(8): 4253-4261.
35.	Yoon S, Hong WP, Joo H, et al. Long-term incidence of chronic postsurgical pain after thoracic surgery for lung cancer: A 10-year single-center retrospective study. Reg Anesth Pain Med, 2020, 45(5): 331-336.
36.	Kwon AH, Flood P. Genetics and gender in acute pain and perioperative opioid analgesia. Anesthesiol Clin, 2020, 38(2): 341-355.
37.	Mapplebeck JCS, Dalgarno R, Tu Y, et al. Microglial P2X4R-evoked pain hypersensitivity is sexually dimorphic in rats. Pain, 2018, 159(9): 1752-1763.

1. Gesthalter YB, Seeley EJ. Lung cancer screening. Am J Respir Crit Care Med, 2021, 204(11): 19-20.
2. Adjei AA. Lung cancer worldwide. J Thorac Oncol, 2019, 14(6): 956.
3. Thai AA, Solomon BJ, Sequist LV, et al. Lung cancer. Lancet, 2021, 398(10299): 535-554.
4. Wu F, Wang L, Zhou C. Lung cancer in China: Current and prospect. Curr Opin Oncol, 2021, 33(1): 40-46.
5. Li R, Wang K, Qu C, et al. The effect of the enhanced recovery after surgery program on lung cancer surgery: A systematic review and meta-analysis. J Thorac Dis, 2021, 13(6): 3566-3586.
6. 车国卫. 加速康复外科: 肺癌手术日间化现状与策略. 中国肺癌杂志, 2020, 23(1): 1-4.
7. Hung WT, Cheng YJ, Chen JS. Nonintubated thoracoscopic surgery for early-stage non-small cell lung cancer. Gen Thorac Cardiovasc Surg, 2020, 68(7): 733-739.
8. Novellis P, Maisonneuve P, Dieci E, et al. Quality of life, postoperative pain, and lymph node dissection in a robotic approach compared to VATS and OPEN for early stage lung cancer. J Clin Med, 2021, 10(8): 1687.
9. Jiang Y, Su Z, Liang H, et al. Video-assisted thoracoscopy for lung cancer: Who is the future of thoracic surgery? J Thorac Dis, 2020, 12(8): 4427-4433.
10. Sihoe ADL. Video-assisted thoracoscopic surgery as the gold standard for lung cancer surgery. Respirology, 2020, 25 Suppl 2: 49-60.
11. Berfield KS, Farjah F, Mulligan MS. Video-assisted thoracoscopic lobectomy for lung cancer. Ann Thorac Surg, 2019, 107(2): 603-609.
12. Chie WC, Yang CH, Hsu C, et al. Quality of life of lung cancer patients: Validation of the Taiwan Chinese version of the EORTC QLQ-C30 and QLQ-LC13. Qual Life Res, 2004, 13(1): 257-262.
13. 戴文清. 肺癌病人生活质量量表QLQ-C30和QLQ-LC13中文版的考评及其临床应用. 中山大学, 2006.
14. Basch E, Deal AM, Dueck AC, et al. Overall survival results of a trial assessing patient-reported outcomes for symptom monitoring during routine cancer treatment. JAMA, 2017, 318(2): 197-198.
15. Wilczynski O, Boisbouvier A, Radoszycki L, et al. Integrating quality of life in the care pathway of cancer patients undergoing immunotherapy treatment: Descriptive, cross-sectional survey of an online patient community’s experiences and expectations. J Med Internet Res, 2022, 24(1): e25792.
16. Wang B, Hao N, Zhang X. Factors influencing the psychology and quality of life in lung cancer patients. Saudi Med J, 2017, 38(9): 948-951.
17. 张缜, 张月峰, 王明博, 等. 肺癌患者术后生活质量影响因素的回归分析. 中国卫生统计, 2020, 37(6): 923-925.
18. 秦露露, 封艳辉. 某三级甲等医院肺癌住院患者生活质量及其影响因素. 解放军护理杂志, 2019, 36(1): 38-42.
19. Pompili C, Rogers Z, Absolom K, et al. Quality of life after VATS lung resection and SABR for early-stage non-small cell lung cancer: A longitudinal study. Lung Cancer, 2021, 162: 71-78.
20. Dai F, Meng S, Mei L, et al. Single-port video-assisted thoracic surgery in the treatment of non-small cell lung cancer: A propensity-matched comparative analysis. J Thorac Dis, 2016, 8(10): 2872-2878.
21. Ha DM, Prochazka AV, Bekelman DB, et al. Modifiable factors associated with health-related quality of life among lung cancer survivors following curative intent therapy. Lung Cancer, 2022, 163: 42-50.
22. Chen R, Tang LH, Sun T, et al. Mechanism and management of fentanyl-induced cough. Front Pharmacol, 2020, 11: 584177.
23. White PF, Tang J, Wender RH, et al. Desflurane versus sevoflurane for maintenance of outpatient anesthesia: The effect on early versus late recovery and perioperative coughing. Anesth Analg, 2009, 109(2): 387-393.
24. Xie MR, Zhu YF, Zhou MQ, et al. Analysis of factors related to chronic cough after lung cancer surgery. Thorac Cancer, 2019, 10(4): 898-903.
25. Cata JP, Keerty V, Keerty D, et al. A retrospective analysis of the effect of intraoperative opioid dose on cancer recurrence after non-small cell lung cancer resection. Cancer Med, 2014, 3(4): 900-908.
26. Wang J, Liu L, Song Y, et al. Current understanding on perioperative management in lung cancer: Implications for anesthetic considerations. Drug Des Devel Ther, 2021, 15: 835-842.
27. Zheng C, Wang J, Xie S. Ultrasound-guided thoracic paravertebral nerve block on postoperative pain, quality of life, and recovery in patients with non-small-cell lung cancer. Biomed Res Int, 2021, 2021: 6692815.
28. Riedl D, Gastl R, Gamper E, et al. Cancer patients’ wish for psychological support during outpatient radiation therapy: Findings from a psychooncological monitoring program in clinical routine. Strahlenther Onkol, 2018, 194(7): 655-663.
29. 朱富忠, 盛奇伟, 顾文英, 等. 社会工作视阈下癌症患者心理支持服务模式. 解放军医院管理杂志, 2017, 24(6): 538-541.
30. Wang L, Wang Z. Research on the quality hospice care of elderly cancer patients in China under social work intervention. Environ Health Prev Med, 2020, 25(1): 36.
31. Parker Oliver D, Washington KT, Benson J, et al. Facebook online support groups for hospice family caregivers of advanced cancer patients: Protocol, facilitation skills and promising outcomes. J Soc Work End Life Palliat Care, 2022, 18(2): 146-159.
32. Mogavero MP, DelRosso LM, Fanfulla F, et al. Sleep disorders and cancer: State of the art and future perspectives. Sleep Med Rev, 2021, 56: 101409.
33. Anderson KO, Getto CJ, Mendoza TR, et al. Fatigue and sleep disturbance in patients with cancer, patients with clinical depression, and community-dwelling adults. J Pain Symptom Manage, 2003, 25(4): 307-318.
34. Koch M, Hjermstad MJ, Tomaszewski K, et al. Gender effects on quality of life and symptom burden in patients with lung cancer: Results from a prospective, cross-cultural, multi-center study. J Thorac Dis, 2020, 12(8): 4253-4261.
35. Yoon S, Hong WP, Joo H, et al. Long-term incidence of chronic postsurgical pain after thoracic surgery for lung cancer: A 10-year single-center retrospective study. Reg Anesth Pain Med, 2020, 45(5): 331-336.
36. Kwon AH, Flood P. Genetics and gender in acute pain and perioperative opioid analgesia. Anesthesiol Clin, 2020, 38(2): 341-355.
37. Mapplebeck JCS, Dalgarno R, Tu Y, et al. Microglial P2X4R-evoked pain hypersensitivity is sexually dimorphic in rats. Pain, 2018, 159(9): 1752-1763.

Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Quality of life and influencing factors in lung cancer patients after video-assisted thoracic surgery

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