• Department of Hepatobiliary and Pancreatic Surgery, Ganmei Hospital Affiliated to Kunming Medical University, Kunming 65000, Yunnan Province, China;
CHENGang, Email: chengang201501@126.com
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Objective To summarize the changes and mechanism of related genes induced by stem cell therapy in acute-on-chronic liver failure (ACLF) in recent years, and in order to guide the clinical value of ACLF and curative effect evaluation. Methods Through searching Wanfang med, CNKI, Pubmed database and so on in recent years, the differentially expressed genes induced by stem cell therapy for ACLF in recent years was retrieved and the changes of related genes induced during the treatment process were discussed. Results Both at home and abroad had reported that stem cell therapy in the process of ACLF caused mir-27b, TRAIL, and Tg737 genetic changes, some genetic changes had an fixed change trend. Conclusions Stem cells in the treatment of ACLF, cause mir-27b, TRAIL, Tg737 genetic changes, which can provides a new way and method for monitoring stem cell therapy ACLF.

Citation: MA Lin-jie, CHEN Xiao, ZOU Long, CHEN Gang, LIU Hong. Research Progress on Related Gene of Stem Cell Therapy for Acute-on-Chronic Liver Failure. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2016, 23(10): 1276-1279. doi: 10.7507/1007-9424.20160327 Copy

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