FANG Cheng 1,2,3 , WANG Piao 1,2,3 , LI Bo 1,2,3 , SU Song 1,2,3 , CHENG Zhen 4 , GAN Yu 1,2,3 , YANG Xiaoli 1,2,3 , PENG Fangyi 1,2,3 , SUO Yongkuan 4
  • 1. Department of General Surgery (Hepatobiliary Surgery), The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, P. R. China;
  • 2. Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province, Luzhou, Sichuan 646000, P. R. China;
  • 3. Academician (Expert) Workstation of Sichuan Province, Luzhou, Sichuan 646000, P. R. China;
  • 4. Molecular Imaging Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, P. R. China;
SUO Yongkuan, Email: suoyongkuan@simm.ac.cn
near-infrared fluorescence; projection imaging; surgical navigation; liver cancer
10.7507/1007-9424.202206071
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Objective  The aim of this article is to verify the clinical effect of the near-infrared fluorescent liver cancer surgery projection navigation system without display screen. Methods  Three patients who need to undergo open hepatectomy for liver cancer in the Affiliated Hospital of Southwest Medical University from March 2021 to May 2021 were included, verifying the accuracy, stability, and time delay effect of the self-developed near-infrared fluorescence projection navigation system for the location of tumor in surgeries. Results  The intraoperative tumor location could be accurately displayed by the near-infrared fluorescence projection system and there was no significant difference between the location of the tumor displayed by intraoperative ultrasound. The tumor location displayed by the near-infrared fluorescence projection system was not influenced by the tumor movement and had no visual-time delay. Postoperative pathology confirmed that the projection range was consistent with the tumor range. Conclusion  This near-infrared fluorescence projection technology innovates the intraoperative tumor imaging mode and can accurately navigate open hepatectomy in small sample trials, and it is expected to achieve wide clinical application through subsequent iterative optimization and verification.

Citation： FANG Cheng, WANG Piao, LI Bo, SU Song, CHENG Zhen, GAN Yu, YANG Xiaoli, PENG Fangyi, SUO Yongkuan. The first clinical verification of near-infrared fluorescence projection navigation technology in liver cancer surgery. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2022, 29(8): 1001-1005. doi: 10.7507/1007-9424.202206071 Copy

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