• Department of Colorectal Surgery, The Forth Affiliated Hospital, China Medical University, Shenyang 110032, Liaoning Province, China;
LI Chunyu, Email: lcy133000@163.com
Export PDF Favorites Scan Get Citation

Objective  To explore the value of fecal calprotectin (FCP) in the activity evaluation for ulcerative colitis (UC).
Methods  Sixty three patients with UC (UC group) and 30 patients with gastrointestinal symptoms but without abnormal results of colonoscopy (control group), who were treated in The Forth Affiliated Hospital of China Medical University between Sep. 2007 to Dec. 2009 were enrolled to examine the FCP, C-creative protein (CRP), and erythrocyte sedimentation rate (ESR). Then comparison between UC group and control group was performed.
Results Levels of FCP and CRP in active gradeⅠ,Ⅱ, and Ⅲ group were all significantly higher than those of control group and inactive UC group (P<0.05), with the increase of active grade of UC, the level of FCP gradually increased (P<0.05). The levels of CRP in active grade Ⅱ and Ⅲ group were all significantly higher than those of gradeⅠgroup (P<0.05), but didn’t differed between active grade Ⅱ and Ⅲ group (P>0.05). There were no significant difference among 5 groups on ESR (P>0.05). Levels of FCP (rs=0.807, P<0.01), CRP(rs=0.651, P<0.01), and ESR (rs=0.371, P<0.05) in active grade group were significantly related to histological grade under colonoscopy.
Conclusion  FCP examination is simple, inexpensive, repeatable, and noninvasive, and FCP can be used as an marker of activity evaluation in UC.

Citation: KUAI Guohu,LI Chunyu,.. Value of Fecal Calprotectin in Activity Evaluation of Ulcerative Colitis. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2013, 20(6): 648-651. doi: Copy

  • Previous Article

    Surgical Treatment of Stanford Type A Aortic Dissection
  • Next Article

    右冠状动脉左心房瘘结扎术后并发脑梗死一例