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find Keyword "诊断准确性" 11 results
  • Evaluation of the Paper Titled “Application of Tumor Type M2 Pyruvate Kinase in Diagnosis of Lung Cancer” Based on the STARD Statement

    Objective To evaluate whether the paper titled “Application of tumor type M2 pyruvate kinase in the diagnosis of lung cancer” met the standards set in the STARD statement. Methods Based on each of the 25 items of STAndards for the Reporting of Diagnostic accuracy studies (STARD statement), the paper titled “Application of tumor type M2 pyruvate kinase in the diagnosis of lung cancer” was checked and evaluated. Results In the paper titled “Application of tumor type M2 pyruvate kinase in the diagnosis of lung cancer”, the reporting of 1 item of the STARD statement was adequately standardized, 7 items were relatively standardized, 5 items were inadequately standardized, 2 items were not standardized, and the other 10 were not reported. Conclusion  Generally speaking, the reporting of diagnostic accuracy studies has not been standardized adequately in China. The methodological quality and applicability of diagnostic accuracy studies should be improved.

    Release date:2016-08-25 03:36 Export PDF Favorites Scan
  • Diagnosis Value of Soluble Triggering Receptor Expressed on Myeloid Cells-1 for Ventilator- Associated Pneumonia: A SystematicReview

    Objective To evaluate the accuracy of soluble triggering receptor expressed on myeloid cells-1 ( sTREM-1) as a diagnostic index for ventilator-associated pneumonia ( VAP) . Methods We searched the PubMed, EMBase, Cochrane Library,Wanfang Database, CNKI and VIP for clinical trials which assessed the diagnosis accuracy of sTREM-1 for VAP. The methodological quality of each study was assessed by the quality assessment for studies of diagnostic accuracy ( QUADAS) tool. The Meta-disc software was used to conduct merger analyses on sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, and diagnostic odds ratio. The heterogeneity test was performed and summary receiver operating characteristic ( SROC) curve was completed. Results 8 studies were included ( 180 VAP patients and 224 non-VAP patients) . The value of merger sensitivity, specificity, and diagnostic odds ratio were 0. 80, 0. 74, and 13. 89, respectively. The area under of SROC curve was 0. 857, with Q point at 0. 788. Conclusion sTREM-1 showed moderate accuracy for VAP diagnosis in adult mechanically ventilated patients, which should be combined with other diagnostic markers to further improve the sensitivity and specificity.

    Release date:2016-09-13 03:51 Export PDF Favorites Scan
  • Application of GRADE in Systematic Reviews of Diagnostic Accuracy Tests: A Case Analysis

    The approaches of rating the quality of evidence of systematic reviews of diagnostic accuracy tests are different from systematic reviews of interventional studies. This article systematically introduces the application of GRADE in systematic reviews of diagnostic accuracy tests by a case interpretation and analysis. In this article we present rating workflow in systematic reviews of diagnostic accuracy tests and introduce how to use the GDT website to display the rating results, and interpret the conclusion of systematic reviews based on GRADE results.

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  • Implement Meta-analysis of Diagnostic Accuracy Tests Using mada Package of R

    The mada package is a type of package that is especially used for implementing meta-analysis of diagnostic accuracy tests. This package is developed on basis of classical statistical theories and it can be used to calculate all relevant effect size of diagnostic accuracy tests; however, it does not provide pooled values of sensitivity and specificity. This article uses an example to introduce the whole functions of mada package in implementing meta-analysis of diagnostic accuracy tests, including data preparation, calculation implementation, result summary, and plots drawing.

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  • Introduction and Explanation of the Updated Standards for Reporting Diagnostic Accuracy Studies (STARD 2015)

    The Standards for reporting diagnostic accuracy studies (STARD) 2015 is a revision of the STARD 2003 on the checklist and flow chart, on the basis of the new evidences of potential bias and applicability, to better guide the application of diagnostic test in clinical practices. Currently, the interpretation and application in China is still based on STARD 2003. This review will describe the application status of the original version and introduce the updated standards for reporting diagnostic accuracy studies.

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  • The Introduction of STARD 2015 for Reporting Diagnostic Accuracy Studies

    The standards for reporting of diagnostic accuracy (STARD) was developed for guiding the reporting of diagnostic accuracy studies. Its newest version was published in 2015. The study mainly introduced the checklist, terminology, and diagram of the STARD 2015. It is hoped that domestic researchers could use the STARD 2015 to guide the implementation and reporting of their diagnostic accuracy studies, so as to improve the reporting quality of diagnostic accuracy studies.

    Release date:2016-10-26 01:44 Export PDF Favorites Scan
  • Interpretation of Standards for Reporting of Diagnostic Accuracy (STARD) for Abstracts

    The standards for reporting of diagnostic accuracy for studies in journal or conference abstracts (STARD for Abstracts) was developed for guiding the reporting of abstracts of diagnostic accuracy studies, which was published in BMJ in August 2017. The study mainly introduced and interpreted the items of STARD for Abstracts, in order to help domestic researchers to perform and report the abstracts of diagnostic accuracy studies by STARD for Abstracts.

    Release date:2017-09-15 11:24 Export PDF Favorites Scan
  • 癫痫患者的抑郁筛查工具:对已验证工具的系统评价

    抑郁影响约 25% 的癫痫患者。然而,癫痫中筛查抑郁的最佳工具尚未明确。研究的目的是系统筛查关于抑郁筛查工具在癫痫中有效性的文献。搜索MEDLINE、EMBASE 和 PsycINFO 数据库时间截至 2016 年 4 月 4 日,对国家或出版语言没有限制。摘要、全文筛查和数据提取由两名研究者进行。 纳入了在癫痫中评估抑郁筛查工具有效性,并报道了诊断准确性(例如,敏感性、特异性以及阴性和阳性预测值)的研究。使用诊断准确性研究的质量评估第 2 版评估研究质量。适当时,计算诊断准确性的估计中位数和范围。共筛选 16 070 篇摘要,其中 38 篇符合纳入标准。 16 种筛选工具在 13 种语言的文章中验证了。 最常用的筛查工具是神经系统疾病伴抑郁量表-供癫痫患者使用(Neurological disorders depression inventory for epilepsy,NDDI-E)(n=26)。简明国际神经精神访谈(Mini international neuropsychiatric interview,MINI)(n=19)是最常用的参考标准。在最常见的截点>15(n=12)中,NDDI-E 的中位灵敏度为 80.5%(范围 64.0~100.0),特异性为 86.2%(范围 81.0~95.6)。由于评估截点的多变性、参考标准的使用以及缺乏置信区间(CI)报告,Meta 分析不可行。许多研究证实了抑郁筛查工具,然而,关于诊断准确性的评估报道不一。在实践中,量表的有效性可能被高估了,因为截点常常是基于研究样本事后选择的。虽然,最佳工具的选择可能因使用环境和可用资源而异,但执行良好的 NDDI-E 是最常用的有效的筛查工具,它向公众免费开放,并经多种语言验证,且易于管理。

    Release date:2018-09-18 10:17 Export PDF Favorites Scan
  • Methods of data extraction in meta-analysis of diagnostic accuracy study

    Receiving the amount of true positives, false positives, false negatives and true negatives is necessary when conducting meta-analysis of diagnostic tests. Advanced methods of data extraction are required if these data could not be directly obtained from a literature. We introduced three methods and discussed the theories. An example was then given to illustrate how to apply the methods.

    Release date:2018-09-12 03:22 Export PDF Favorites Scan
  • Interpretation and assessment of reporting guideline of systematic review/meta-analysis for diagnostic test accuracy study (PRISMA-DTA)

    The PRISMA-DTA Statement is an expanded checklist of the original PRISMA, which is aimed at improving the reporting quality of the systematic review or meta-analysis of diagnostic test accuracy studies. It was published on JAMA in January 2018. This paper explained it and provided reference for improving the reporting quality of systematic review/meta-analysis of DTA for Chinese authors.

    Release date:2018-09-12 03:22 Export PDF Favorites Scan
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